Plextronics was founded in with the goal of taking conductive polymer technology that McCullough developed to commercial uses. Babe said Liquid X's priority is to identify its first commercial applications and generate volume business. Liquid X's technology clearly has a cost advantage because it produces thinner trace lines using gold or silver.
Article courtesy of Popcity. Beginning in August, Acrobatiq will look to bring a different approach to improving learning outcomes in higher education to a much wider audience. A spinoff from Carnegie Mellon University's Open Leaning Initiative, Acrobatiq will offer customizable courseware, learning analytics and consulting services to educational institutions looking to improve learning outcomes for students. The OLI approach, which was developed by CMU and focuses on building learner-centered courseware that is informed by the science of learning, will serve as the foundation of Acrobatiq's methodologies.
The company said its formation will accelerate the pace of innovation and provide a financially sustainable model to develop courses and analytics more quickly, while also making them more widely available to four-year universities, community colleges and for-profit schools across the country. Several key members of the former OLI team will serve on Acrobatiq's management team.
The company said they are committed to supporting current OLI users without interruption and will honor all existing agreements between OLI and institutions, even those that were discounted or free. Additionally, the company will continue to maintain a catalog of free and openly licensed courses and make its tools available to education researchers at no cost. Blue Belt Technologies Inc. The NavioPFS provides precise robotic control to surgeons performing minimally invasive surgeries via an intelligent, handheld, computer-assisted bone-cutting tool.
Kevin Lester performed the nation's first partial knee replacement surgery with the system in February. The company, with offices in Pittsburgh and Plymouth, Minn. Eleven of Blue Belt's staff members are CMU alumni, including the following management team members and adviser:. Article courtesy of CMU News. Doug was born with a congenital defect that gave him a 2 percent chance for survival.
Resolving congenital conditions like his has remained ever-present for Doug, who is now a year old Carnegie Mellon biomedical and mechanical engineering graduate laboring to solve clinical problems with his startup Peca Labs for pe diatric ca rdiology.
These young entrepreneurs are not the products of cynical experience, and they have a long path ahead to success. But they also have the energy and the runway to get there — with the right support and help. These young folks are part of a breed of innovators that we, as a nation, must support and encourage. They are the product of engineering and other technical programs at our great research universities, and they are choosing the road less traveled. It is up to us to guide them along that path, to help them improve healthcare options, and to use innovation and entrepreneurship to make our nation more competitive — for the betterment of the human condition.
Why entrepreneurship? Many newly minted engineers like Doug are choosing the entrepreneurial path over advanced degrees and other opportunities because a startup is the only way they can get their ideas to patients. But he has always walked the unbeaten path. By second grade, Doug was determined to be a genetic engineer — yes, you read right: second grade! Competitive with his older brother, precocious Doug learned to read, write and study at an early age — three to be exact.
By age eight, Doug was devouring books on science and genetics. He is enthralled by the concept of small robots that can improve human health, like the pill camera that visualizes your GI track. He had several research projects going at any one time, starting from his freshman year. Doug was hunting for a project that he could sink his teeth into, something that spoke to him, to his heart — literally. One of his research projects involved inventing and testing new heart valves with Kerem Pekkan , Ph.
Masahiro Yoshida Masa. Masa had been utilizing several new designs and materials for pediatric right ventricular outflow tract RVOT reconstruction and had been searching for a valve that provided some flexibility and better resistance to calcification so that, as the baby grew, the valve would continue to be valid. Otherwise, the state-of-the-art valve becomes hardened and narrow over time. This means multiple surgeries and valve replacements as a baby grows through youth and into adulthood.
These procedures are costly, dangerous, invasive and highly inefficient, even while they were clinically effective. Having developed components for a new valve, Masa used them in 50 surgeries to date — all with excellent clinical results. Invention to Innovation With his engineering mindset and the lead taken by his CMU engineering professor, Doug and the team came up with a novel design for a synthetic valved conduit — the Masa Valve — that improved on the components started by Masa.
At the same time, Doug, by then a junior, took a class in robotics ventures that focused on real world applications of robotics. It seemed like he had been up for days—he looked exhausted. But he wanted advice badly and he was willing to spend a summer investigating the market side of his heart valve idea. I spotted the heart and drive of an entrepreneur in Doug. While his stubbornness infuriated me, I respected his commitment to learn and dedication to the project.
Doug had no clue about the FDA, reimbursement, startups, markets, business or funding. He had no money, no way to eat or pay rent. I worked with our administration to get him GAP funds to pay himself to work on the project for the summer. I wanted him fully committed with no second job that paid his rent. By the end of the summer, he had the beginnings of a market understanding.
He had talked with some of the cardiothoracic surgeons nationwide who each perform 32 surgeries per year. He talked to hospital systems, insurance companies and the FDA. He started that fall by taking a class that I co-taught with Dave Mawhinney head of the Don Jones Center for Entrepreneurship in basic entrepreneurship for engineers Introduction to Technology Entrepreneurship for Engineers.
Doug had decided over the summer that he wanted to give an entrepreneurial go of it. He had co-authored a paper on the heart valve concept as lead author — impressive for an undergrad. He had also put out a poster for the Society of Thoracic Surgeons.
Confident in his technical abilities, the entrepreneurship class was a means for Doug to learn what he needed to do to hone in on the business aspects of starting and growing a business. Doug used his final semester at CMU to take an independent study with me — that semester was all about Peca and getting it off the ground. Today After graduating in Mary , Doug deferred a Ph.
He recruited fellow CMU alums, Jamie Quinterno history and business; also my student , and Arush Kalra, MD current masters student in biomedical engineering and former pediatric urological surgeon to join the startup and they began operations. Challenges Peca has a long road to hoe, between attempting FDA approval, finding manufacturers, and other milestones. However, Doug is determined to help the 3, children per year who require RVOT reconstruction, each of whom will need three to four open-heart surgeries over the course of their growth.
The company still has to prove safety and benefits to achieve a Humanitarian Device Exemption HDE so that they can sell the devices. Peca faces all kinds of manufacturing, IP, and licensing challenges. The company has come far since Doug entered my office almost two years ago.
Doug has come far personally. His journey is not over, but his eyes are wide open to the possibilities. If Peca achieves its goal of bringing this valve to market, the company will establish a new precedent for bringing orphan devices to market. As a niche player with streamlined processes, Peca should be an attractive acquisition target.
Entrepreneurship Education in Engineering Entrepreneurship has given Doug the opportunity to expand his horizons in a way that can impact thousands of young children who need heart surgery. It has literally changed his life.
And we should realize that there are thousands, maybe even tens of thousands, of Dougs on campuses across the nation. Instilling the entrepreneurial spirit in students like Doug, giving them the tools they need to take products to market, encouraging and unleashing innovation and entrepreneurship benefits not only those students, but the universities, the nation and humankind.
It is up to universities to recognize the importance of integrating entrepreneurship training deeply into the fabric of their course and program offerings. You learn to focus on making the technology work, but you never learn to focus on why make it work. You can go through four or five years of work, and what you create may never help anyone.
The questions are never asked. It would bring in the actual world, not theoretical world. Article courtesy of Epicenter. Researchers at Carnegie Mellon University are working on edible electronic devices that can be taken to monitor people's health and improve patient care. These electronic pills could perform functions like targeted drug delivery for certain types of cancer, stimulate damaged tissue, measure biomarkers or monitor gastric problems.
But before these pills are actually possible, an edible power source is needed to charge the pills. That's where Bettinger and his fellow researcher Jay Whitacre, a professor of materials science and engineering, come in. Bettinger and Whitacre have created an edible battery that is taken in the form of a pill that produces the same kind of currency as a regular battery that powers, let's say, a wrist watch.
But the pill battery is made entirely of biodegradable material that is already found in the human body. While the digital pills that can perform varied functions inside the body are still in the works, the edible battery helps pave the way for further development. Bettinger and his fellow researchers are working with the start-up incubator Incubation Works to get their battery pill out of the research stage so that new kinds of digital pills can be developed.
Article courtesy of CNBC. Celsense, Inc. The Phase 1 clinical trial was cleared by the US FDA for the purposes of developing information regarding cell migration following administration of live cells. This application, involving the use of an autologous dendritic cell vaccine to treat colorectal cancer, is the first time the trafficking of a live cell cancer vaccine in patients has been visualized by MRI in the United States.
The administration of live cell vaccines is an emerging strategy to treat a variety of cancers. Investigators believe that the unaided trafficking of dendritic cells to the lymph node is fundamental to the success of this therapeutic strategy. While this is only the first patient to be imaged in the clinical trial, we expect that data from this study as a whole will lead to improved outcomes for patients receiving live cell vaccines for cancer," said Charlie O'Hanlon, President and CEO of Celsense.
Pawel Kalinski and David Bartlett. Other investigators include Dr. Amy Wesa at Celsense. Article courtesy of PRWeb. The funding will allow Neon to continue developing a product that automatically selects the most visually appealing frame from a stream of online video to be used as the video's thumbnail. Thumbnails—the entry points for Web users to interact with videos—are becoming more important to video publishers as the number of online videos increases.
True is thrilled to support this groundbreaking company. Against a randomly generated thumbnail, which is how the majority of online video platforms select thumbnails, Neon's thumbnail increased the clicks even more. The current beta testing period will give Neon even more insight into how the product can increase user engagement.
Eventually, Neon aims to apply the same technology to improve image selection across a variety of Web services, such as, connected TV, photo sharing, e-commerce and advertising. Lipinski continued, "When I saw the Neon team's ideas at the final I-Corps presentation last year, I knew that big things were ahead.
I look forward to watching as I-Corps helps turn more federally funded research into products that promote economic development and boost American competitiveness. The investment we make is minimal compared to the potential returns in American jobs. Neon's success is more proof that I-Corps is something that should be expanded to other agencies throughout the federal government.
The underlying technology is co-owned through Carnegie Mellon and Brown University and licensed through Carnegie Mellon. I am confident that with this team and our academic partners from Brown and CMU, Neon will be able to create products that transform how online images are selected. The university's Greenlighting Startups initiative is designed to speed innovations from the lab to the marketplace. In the past 15 years, Carnegie Mellon faculty and students have helped to create more than companies and 9, jobs.
The university averages 15 to 20 new startups each year. Article courtesy of Phys. It has the connections of Kleiner Perkins, the cachet of Bill Gates and the dollars of a quickly growing Russian venture capital firm. Another new funder for the battery maker is Chicago-based Gentry Venture Partners, which focuses on green energy investments and frequently co-invests with Kleiner Perkins.
The final close is expected in May. Bright Capital, which also has an office in California, describes itself as a merchant venturing entity: It provides not only funding but also works to link its portfolio companies with industrial connections in Russia and other former Soviet countries.
It has about employees to date. It has only been a few months since DARPA announced the teams competing in its upcoming Robotics Challenge , but already some of the robots are beginning to shape up. The idea is to take advantage of both legged and wheeled locomotion, allowing the robot to scoot around low to the ground but stand up when necessary.
While famous bipedal robots like Honda's Asimo do a good job of replicating this behavior in structured environments like office buildings, it's a different story when they're faced with a steep, rocky hill. The CHIMP's unusual approach to locomotion should allow it to rapidly overcome these obstacles, even if it is only stable in a static way.
Each of those seven teams is taking a different approach to the design and functionality of their robots. A second group of teams will use a version of Boston Dynamics' humanoid robot Atlas. One thing that all of the robots participating in the competition will share in common is that they're remote-controlled by people.
In a pinch, it can do anything. The harsh reality for sci-fi fans is that today's artificial intelligence hasn't come far enough for robots to carry out chains of highly complex tasks without human assistance. An operator will control CHIMP using a keyboard and mouse at a workstation consisting of a large monitor displaying multiple video feeds from the robot's cameras, and software with shortcuts to easily shift from manual to autonomous control.
The robot's sensors will generate a texture-mapped 3D model of its environment, enabling the operator to visualize the robot's position relative to its surroundings. A nice side-effect of building the robot is the development of new technologies, such as the proprietary drive joints [pictured below] seen in its arms and legs that possess near-human strength and dexterity, can be implemented in a diverse range of robots such as those intended for manufacturing.
In the coming weeks and months we're expecting to learn more about the other teams' robots. If all goes well, robots like those developed for the challenge will one day take the place of people in life-threatening circumstances. Blue Belt Technologies, Inc. The NavioPFS surgical system represents the next generation of precision orthopedic surgery, with an initial indication for use in UKR procedures, and a wide array of future applications in development. Lester, an orthopedic surgeon at Community Regional.
Using the NavioPFS, this step is seamlessly integrated into the system, and the robotic handpiece allows for precise and repeatable bone preparation. I am looking forward to continuing to offer this new and excellent option to my patients.
Utilizing the integrated CT-free navigation system with intraoperative registration and planning, Dr. Lester successfully planned two left-medial and one right-medial partial knee replacement surgeries and executed bone preparation through a less-invasive incision using the NavioPFS precision freehand sculpting handpiece. Friedman, with more than 15 years of experience at various Portland startups, replaces company co-founder Henry Hillman Jr.
And he expects Friedman to lead that growth. The startup's imaging system has helped make about , highly detailed images for a large array of institutions and businesses, including NASA, National Geographic, Sports Illustrated, Major League Baseball and assorted educational and research institutions. Friedman says one of his major initiatives will be to build revenue and find new clients as well as deepen existing relationships, including the company's connections to sports teams.
Friedman envisions a scenario in which every major sports team uses the GigaPan system, for example. An Oregon State University graduate, Friedman's last gig was chief operating officer of the music licensing company Rumblefish. He's well known in the local startup community and possesses layers of connections to its network of players, technical talent and, perhaps most importantly, to a growing company like GigaPan, its investors.
Article courtesy of Oregon Live. Every new glimpse at the future of urban transport seems to be missing something pretty big. A trains of cars commuting on the highway with human drivers who aren't, you know, actually driving. The next peek ahead, according to computer scientist Ozan Tonguz of Carnegie Mellon University, gets rid of all the traffic lights.
At least the physical ones. Tonguz and colleagues are designing a road-efficiency system, based on emerging-vehicle-to-vehicle technology, called Virtual Traffic Lights. The idea is to shift traffic control from fixed street signals to the moving cars themselves. The result, says Tonguz, is an optimized traffic flow that should greatly reduce city congestion.
The virtual system processes this information for all the cars in the area, with the help of a lead car that changes every cycle, and determines your individual traffic signal. Instead of seeing a red or green light hanging in the intersection, you see it on your windshield and stop or go accordingly.
The first advantage to Virtual Traffic Lights is that every intersection with a car now automatically has a traffic light. That may not seem like much, but fewer intersections are equipped with signals than many people realize. In New York City, for instance, only about 24 percent of intersections have a four-way signal.
As traffic lights become ubiquitous, road safety should dramatically improve. The second benefit is a much better traffic flow. The algorithm that governs the virtual system can be written for total efficiency. If the system recognizes that no cars are coming from another direction, it can extend a green signal indefinitely. Likewise, at heavy intersections, it can give preference to the longest line of cars.
Using similar technology to Google's driverless car, the system can also recognize the presence of pedestrians and bicyclists, and orchestrate traffic to suit their needs. In recent simulations the system has performed quite well. The flow of cars in Porto — the second-largest city in Portugal, with 16 percent signal coverage at intersections — improved by 60 percent during a rush-hour scenario of one test [ PDF ].
The Virtual Traffic Lights system has even beaten congestion pricing models "hands down," Tonguz says. Tonguz drew inspiration for the virtual system from nature. His idea was to capture the basic rules of self-organization practiced by biological species and engineer cars to cooperate in a similar manner. If a "colony of vehicles" can act more like a colony of ants, he says, "the lump sum behavior will be much better than we have right now. The basic technology for Virtual Traffic Lights is already here.
Car-to-car conversations can operate over Dedicated Short Range Communication at 5. Tonguz expects D. His work is being sponsored by the Department of Transportation, and Tonguz says he's also received funding from General Motors throughout his career.
The biggest obstacle, says Tonguz, is getting the government to test the system in a real-world setting. Compared to software startups, life sciences companies can take a longer time frame and more capital to get off the ground. Pressure ulcers affect 2. So far, Gaspard, who started working on this project while a doctoral student in biomedical engineering at Carnegie Mellon University , has created a lab prototype of the system. But to secure funding to take the device forward, she needs a clinical prototype.
To get the clinical prototype, she still needs funding. The device uses a specific type of spectroscopy that uses light to inspect tissue. The device shines light on skin and analyses the light reflected back, measuring changes in tissue properties and assessing the health of the tissue, Gaspard said.
Pressure ulcers typically hit immobile patients. She knew it would be difficult to raise money. After some early-stage funding fell through, she is now considering taking the company outside of Pittsburgh. She opted to start the company here in order to build on the network she was starting to build as a student plus the lower cost of living is more conducive, she said.
If it works -- and they're convinced it will -- the device could help an estimated 3, children born each year with a specific birth defect to avoid undergoing multiple open heart surgeries as they grow up. Amid bare furnishings, the entrepreneurs often work seven days a week, eating at their desks one of them occasionally naps on a pullout sofa bed after an all-night work session , while earning what one described as "survival wages. It may seem an improbable scenario for advancing the complex world of medical devices.
Larry Miller, life sciences executive-in-residence at Innovation Works, said the trio's comparative inexperience was of little concern in the organization's decision to invest. If there were any hesitation about backing Peca, said Mr. Miller, it was the "relatively small" market the startup was targeting. Developing and marketing a new medical device is usually an expensive proposition, and investors aren't likely to jump in if there's no financial return. The Peca three -- the name is a shortening of "pediatric cardiovascular" -- have addressed that problem by running a super-lean operation.
Their low-rent office space, which amounts to not much more than a couple of work stations and a small conference space in the back, is just one manifestation of that. Quinterno, "we still take turns cleaning the bathroom. They are one-third of the way there, after the Innovation Works investment, and they've only just started to reach out to potential angel investors. Along the way, the doubters have been plentiful. Among the concerns: There are not enough children who have the birth defect, which requires surgical reconstruction of the right ventricular outflow tract, to make the device profitable.
At AIMBE College of Fellows, Fellows are nominated each year by their peers and represent the top two percent of the medical and biological engineering community. The election to the Academy represents a highly selective process, and there are currently about members before the announcement of Class The following are some of Class of Fellows:.
The POLY Fellows Program was established in to recognize excellence in all ways that POLY members advance the field of polymer science, through either scientific accomplishments, service to the profession, or both. Matthew L. Becker works at the interface of chemistry, organic materials, and medicine.
His research focuses on developing families of degradable polymers with highly tunable physical and biological properties that are being applied to unmet needs in bone, soft tissue, and neural and vascular tissue engineering. He is also actively engaged in additive manufacturing and leads the development of custom inks that are enabling unique solutions to challenging problems in biomaterials and drug delivery.
Becker earned a B. Wooley at Washington University in St. Nicholas A. Peppas was elected for his lifetime achievements in the areas of biomaterials, drug delivery, and chemical engineering. He is recognized for his extensive work on the preparation, characterization, and evaluation of biopolymers and hydrogels, used as biomaterials in artificial organs and in devices for the delivery of drugs, peptides, and proteins.
The multidisciplinary approach of his research in biomolecular engineering blends modern molecular and cellular biology with engineering to generate next-generation systems and devices, including bioMEMS with enhanced applicability, reliability, functionality, and longevity. The year has proven to be a challenging year for humanity: volcanic eruptions, bushfires, floods, storms, the melting of glaciers, and the emergence of COVID, which has brought much of the world to a standstill.
The professionals highlighted here are driving the industry forward and saving lives by developing new medicines. Some of these individuals are also lending a helping hand in bringing COVID vaccines and treatments to market. Some of the inspirational medicine makers that were named in the Power list are:. Robert S. Langer, the David H.
Koch Institute Professor at Massachusetts Institute of Technology, is the most cited engineer in history and one of the most prolific inventors in all of medicine. Langer has nearly issued and pending patents, many of which have been licensed or sublicensed to over pharma, chemical, biotech, and medical device companies. He has also founded a number of biopharma companies, including Moderna Therapeutics, which is one of the companies pursuing the development of a COVID vaccine.
Justin Hanes, the Lewis J. His lab discovered methods to make drug- and gene-loaded particles that efficiently penetrate mucus barriers, which may allow for more effective therapies for eye diseases. Hanes received his PhD in chemical engineering from MIT and completed a two-year postdoctoral fellowship in oncology and neurosurgery at Johns Hopkins prior to his initial faculty appointment in Antonios G.
His work has led to the development of orthopedic, dental, cardiovascular, neurologic, and ophthalmologic biomaterials. His vision for advanced medicine focuses on the development of biomaterials to enable engineers, scientists, and clinicians to work collaboratively to create viable tissues and organs. She is the author of over scientific contributions with more than 17, citations and the inventor of 22 patent families.
Alonso is the past president of the Controlled Release Society. She is also an editorial board member of Regenerative Engineering and Translational Medicine.
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